Malaria and Neglected Diseases
Research

Malaria and Neglected Diseases

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This programme aims to expand our current scientific understanding of the most relevant diseases affecting humans, and their host-vector interactions, in order to support evidence-based policy-making for disease control and eventual elimination.

We focus on malaria and neglected diseases such as Chagas, Dengue, soil transmitted helminths and leishmaniasis.

We apply methods which include  immunology, basic cell and molecular biology, omics, epidemiology, intervention trials with drugs, vaccines and diagnostic tools, surveillance and implementation science.

This program has international leadership in:

  • Basic science for a better understanding of the biology and host-pathogen interactions of these diseases.
  • Development and evaluation of new tools /strategies for the treatment and control of these diseases.
  • Surveillance and implementation science.

Capacity building is included at all levels.

Research Groups

Our Team

Leadership

Principal lnvestigators of the Programme

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Highlighted Projects

Manhiça Health Research Centre (CISM), in Mozambique

ASINTMAL

Unravelling Disease Tolerance and Host Resistance in Afebrile 'P. falciparum' Infections: a Prospective Study in Mozambican Adults

MULTIPLY

MULTIple doses of IPTi Proposal: a Lifesaving high Yield intervention

Science4Pandemics Project

Science4Pandemics

Citizens engagement digital platform for collective intelligence in pandemics

BOHEMIA

Broad One Health Endectocide-based Malaria Intervention in Africa

Euroleish.net

Control of Leishmaniasis. From bench to bedside and community

TESEO

New chemotherapy regimens and biomarkers for Chagas Disease

MENA Migrant Health

Transforming data collection and surveillance to drive migrant health research, care and policy

GenMoz

P. falciparum genomic intelligence in Mozambique

MESA

Sharing knowledge and catalyzing research towards a malaria-free world

RTS,S Vaccine Immunology Study

Study of immune correlates of protection against malaria after vaccination with RTS,S/AS01E: a comprehensive immunological arm of a Phase III double-blind, randomized, controlled multi-center trial

Other projects

See Past Projects

HIDDENVIVAX

Novel organ-on-a-chip technology to study extracellular vesicles-mediated cryptic infections in Plasmodium vivax malaria

ADAM

Malaria mass and focal drug administration to advance malaria elimination in Mozambique: accelerating programmatic implementation and policy translation

EpiGen

Building Scalable Pathogen Genomic Epidemiology in Ethiopia

NHEPACHA

New Tools for the Diagnosis and Evaluation of Chagas Disease

SMART

Identifying Severe Malaria with a new Aptamer-based Rapid diagnostic Test