NHEPACHA is an Ibero-American network formed by 12 research groups from 9 countries working in the field of Chagas disease. The network was created to foster research activity and the exchange of knowledge and experiences and to build on the skills needed to develop new tools and biomarkers for the diagnosis, treatment, evaluation and management of Chagas disease and to improve existing ones.
Objectives
- • Establish a research, development and innovation framework to identify potential new drugs as well as biomarkers that will aid in the diagnosis and management of Chagas disease and in the evaluation of new drugs in future clinical trials. Specific actions will include:
- the identification of joint research topics
- the fostering of academic exchanges among researchers
- Promote the exchange of knowledge through:
- training and work exchange programmes for members of the network
- workshops
- the production and dissemination of consensus statements and reviews on topics related to the goals of the network
- Plan operational studies and multicentre clinical trials to test new tools and improve existing ones, through:
- the design and coordination of research projects
- the creation of a standardised database for monitoring patients with Chagas disease
- the transfer of technology to the biomedical industry and national health systems
Members of the network
- IMT-UCV (Instituto de Medicina Tropical, Universidad Central de Venezuela, Venezuela).
- FIOCRUZ-IOC (Fundação Oswaldo Cruz – Instituto Oswaldo Cruz) Brazil.
- ISGlobal (Barcelona Institute for Global Health), Spain
- CIEI-PUCE (Centro de Investigación de Enfermedades Infecciosas de la Pontificia Universidad Católica del Ecuador), Ecuador.
- UA-CIMPAT (Universidad de los Andes), Colombia.
- IPBLN-CSIC. (Instituto de Parasitología y Biomedicina Lopez-Neyra), Spain.
- CRISP –INSP (Centro Regional de Investigación en Salud Pública, Instituto Nacional de Salud Pública), Mexico.
- DNDi (Drugs for Neglected Diseases Initiative).
- INGEBI (Instituto de Investigaciones en Ingeniería Genética y Biología Molecular), Buenos Aires, Argentina.
- CENDIE, (Centro Nacional de Diagnóstico e Investigación de Endemoepidemias), Argentina.
- UMSS. (Universidad Mayor de San Simón), Bolivia.
- HIGA (Hospital Interzonal General de Agudos Eva Perón, Sección Chagas, Servicio de Cardiología), Argentina
- Fundación Mundo Sano, Argentina.
Other projects
See Past ProjectsRTS,S Vaccine Immunology Study
Study of immune correlates of protection against malaria after vaccination with RTS,S/AS01E: a comprehensive immunological arm of a Phase III double-blind, randomized, controlled multi-center trial
Euroleish.net
Control of Leishmaniasis. From bench to bedside and community
GREPIMER
Grup de recerca en patología importada i malaties emergents i re-emergents
TESEO
New chemotherapy regimens and biomarkers for Chagas Disease
ASINTMAL
Unravelling Disease Tolerance and Host Resistance in Afebrile 'P. falciparum' Infections: a Prospective Study in Mozambican Adults
ADAM
Malaria mass and focal drug administration to advance malaria elimination in Mozambique: accelerating programmatic implementation and policy translation
MULTIPLY
MULTIple doses of IPTi Proposal: a Lifesaving high Yield intervention
Science4Pandemics
Citizens engagement digital platform for collective intelligence in pandemics
HIDDENVIVAX
Novel organ-on-a-chip technology to study extracellular vesicles-mediated cryptic infections in Plasmodium vivax malaria
Subclinical Infections in Children and Long Term Health Effects
Infection acquisition in early life and health outcomes in childhood - MARATO TV3
Herramienta innovadora de detección de enfermedades y vacunación a población inmigrante en riesgo en España
Project Code: PI21/00651
Impacto de las coinfecciones en el balance de respuestas de anticuerpos y linfocitos T helper a antígenos diana de inmunidad natural y vacunal frente a patógenos humanos prominentes
Project Code: PI20/00866
EpiGen
Building Scalable Pathogen Genomic Epidemiology in Ethiopia
MalTransc
Transcriptional regulation of adaptation and developmental decisions in malaria parasites: from epigenetic variation to directed transcriptional responses
BOHEMIA
Broad One Health Endectocide-based Malaria Intervention in Africa
RESPONSE
Mechanisms of the transcriptional responses to changes in the environment in the malaria parasite Plasmodium falciparum
VivaxEVTalk
Extracellular Vesicles as Intercellular Communicators and Biomarkers of Cryptic Erythrocytic Infections in Plasmodium vivax malaria
VaMonoS
Unravelling the heterogoneity and function of monocytes in vaccination and immunity to malaria
CLIMSOCTRYPBOL
Insight on climate and social participatory research for integral management of vectorborne zoonosis caused by Trypanosoma cruzi and Leishmania spp. in the Bolivian Gran Chaco.
SexMal
Social affairs and sex in P. falciparum: implications for malaria elimination
MENA Migrant Health
Transforming data collection and surveillance to drive migrant health research, care and policy
MESA
Sharing knowledge and catalyzing research towards a malaria-free world
GenMoz
P. falciparum genomic intelligence in Mozambique
SMART
Identifying Severe Malaria with a new Aptamer-based Rapid diagnostic Test