LeRAgs
Acute Kidney Injury in Agricultural workers in Spain: risk factors and long term effects
- Duration
- 2018-2020
- Coordinator
- Cristina O'Callaghan Gordo (ISGlobal)
- Funded by
- Instituto de Salud Carlos III (ISCIII)
The objectives of this project are:
- to study whether the environmental and occupational conditions to which agricultural workers are exposed during the warmer months in areas of Mediterranean climate, suppose a risk for developing acute kidney injury (AKI)
- if AKI increases the risk to develop chronic kidney disease (CKD), taking into account lifestyle exposures and pre-conditions of health that can modify these risks.
We will conduct a cross-sectional study including agricultural workers of crops requiring different climatic conditions in three provinces of Spain: Alicante, Huelva and Tarragona.
We aim to enrol 600 participants (200 per province) through agricultural cooperatives/companies. We will collect information on the temperature and humidity conditions in the workplace. We will take blood samples at the beginning and end of the working day to detect the presence of AKI using various biomarkers. We will collect information on socio-demographic variables, clinical history and occupational and environmental expositions by performing structured interviews, taking anthropometric measures and monitoring workers during the working day. Participants with AKI detected, and a random selection of participants without AKI, will be re-contacted one year after the start of the study to assess their renal function.
This will be the first study to simultaneously analyse the effect of environmental and occupational exposures on renal function in agricultural workers in Spain.
Total Funding
75.020 euros
Our Team
Principal Investigator (IP)
-
Cristina O'Callaghan Associated Researcher
ISGlobal Team
-
Lourdes Arjona Lab Manager and Research Technician
-
Gemma Castaño Staff Scientist
-
ANNA DELGADO Research Technician
-
Ana Espinosa Statistician
-
Manolis Kogevinas Research Professor
-
Oriana Ramírez Associated Researcher
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