Publicador de continguts

Recerca i Innovació Programes

Global Assessment of Trihalomethanes in Drinking Water

Durada
May 2017 - October 2018
Coordinador
Cristina Villanueva Belmonte (ISGlobal)
Finançadors
Human Genetics Foundation (Turin, Italy) and EC project EXPOSOMICS

Lack of access to improved drinking water sources is still a main problem in many parts of the world, leading to high incidence rates of waterborne infections or sanitation-related diseases.

Chlorination of drinking water is a major public health intervention to provide safe drinking water to the population and control for water-borne infectious diseases. On the other hand, disinfection process with chlorine generates undesired chemical by-products such as trihalomethanes (THMs). In some countries, this environmental exposure can be of concern since the whole population is exposed through ingestion, inhalation and dermal contact, and long-term exposure to THMs has been linked to disease, including bladder cancer.

THM levels in drinking water are regulated in many countries worldwide but are rarely reported in the majority of them and current levels at a global scale are unknown.

Specific objectives

  • To develop a global map of current THM levels in drinking water (total and chloroform, bromoform, dibromochloromethane, bromodichloromethane)
  • To estimate bladder cancer burden attributable to THM levels at a global scale
  • To conduct a comparative risk assessment between bladder cancer attributable to THM levels and water-borne infectious diseases attributed to lack of improved drinking water sources.

In 2016, we conducted the same study for Europe and we are now expanding it to include non-European countries.

The project is led by Dr Cristina Villanueva together with Prof Manolis Kogevinas, Dr Susan Richardson (University of South Carolina) and Dr Stuart Krasner (Metropolitan Water District of Southern California) in the US and is coordinated by Dr Iro Evlampidou. Other close collaborators in the project are Weidong Qu (School of Public Health, Shanghai, China and David Reckhow (University of Massachusetts, US).

Expected impact

This project will provide for the first time a global assessment of current levels of THMs that, surprisingly, do not exist. THM exposure estimates will allow the development of disease risk assessment at a global scale.

Current status of the project

Data collection

 

Open Call for collaborators!

We are looking for collaborators in many countries in the world to provide THM data (total and chloroform, bromoform, dibromochloromethane, bromodichloromethane) (see map below).

Click the following links to see the study protocol and the questionnaire.

If you are interested please contact us at cristina.villanueva@isglobal.org

Acknowledgements

Many thanks to the people who have contributed data or helped us connect with the people who have the data we need!

 

Our Team

Coordinator

ISGlobal Team

Altres projectes

Veure projectes passats

MCC-Spain

Estudi multi-cas control poblacional, incloent tumors d'alta incidència a Espanya

HELIX

Novel tools for integrating early-life environmental exposures and child health across Europe

EGG/EAGLE

Early Genetics Growth/Early Genetics and Lifecourse Epidemiology

PACE

Pregnancy and Childhood Epigenetics

LIFECYCLE

Early-life stressors and LifeCycle health

OMEGA-NET

Network on the Coordination and Harmonisation of European Occupational Cohorts

HARMONIC

Health effects of cArdiac fluoRoscopy and mOdern radIotherapy in paediatriCs

Mobilise-D

Connecting digital mobility assessment to clinical outcomes for regulatory and clinical endorsement

EARLY-ADAPT

Signs of Early Adaptation to Climate Change

COVICAT

Cohorte Covid-19 en Cataluña

ATHLETE

Advancing Tools for Human Early Lifecourse Exposome Research and Translation

CONTENT

Cohort de COVID-19 a Espanya: dinàmica social, salut mental i desigualtats

EUCAN-Connect

A federated FAIR platform enabling large-scale analysis of high-value cohort data connecting Europe and Canada in personalized health

OBERON

An integrative strategy of testing systems for identification of EDs related to metabolic disorders

EXPANSE

EXposome Powered tools for healthy living in urbAN SEttings

AURORA 2021

Actionable eUropean ROadmap for early-life health Risk Assessment of micro- and nanoplastics

ONES

Fine Particle Matter, Fetal Growth, and Neurodevelopment: Examining Critical Windows of Susceptibility

AIR-NB

Pre-natal exposure to urban AIR pollution and pre- and post-Natal Brain development

NutinBrain

The role of seafood and nut consumption on human neurodevelopment from pregnancy to adolescence

UrbanKids

Urban and social environment and childhood obesity – a natural moving2health experiment

iGenCO

In-Depth Genomics and Cross-Omics Analysis for Undiagnosed Rare Diseases on a User-Friendly Collaborative Platform

CityExposomeCat

An Exposome Approach to Urban Health: Individualized Environmental Exposure Assessment in an Adults Population Cohort Study (GCAT)

TwinAir

Digital Twins Enabled Indoor Air Quality Management for Healthy Living

UBDPOLICY

The Urban Burden of Disease Estimation for POLICY Making

TOLIFE

Combining Artificial Intelligence and smart sensing TOward better management and improved quality of LIFE in chronic obstructive pulmonary disease

BWater

Drinking Water in Barcelona: Sustainability and Health Impact Assessment

intoDBP

Innovative Tools to Control Organic Matter and Disinfection Byproducts in Drinking Water

FINDOOR

FTIR spectroscopy for real-time detection of bacterial outbreaks and the rapid identification of pathogenic serotypes, relapsing infections and antibiotic resistance

OccRF-Health

Occupational exposure to radiofrequency electromagnetic fields: From exposure assessment to study of health in workers and their offspring

EPHOR

Exposome Project for Health and Occupational Research

EXPONIT

Analysing and studying how night shift work affects workers' circadian rhythms and health

IHEN

International Human Exposome Network

B-Triage

Una prueba en el punto de atención para la estratificación del riesgo de los pacientes febriles basada en los niveles de sTREM-1

e-QuoL

e-health tools to promote Equality in Quality of Life for childhood to young adulthood cancer patients, survivors and their families

AM-MENTAL

Com afecta la teva salut mental que el teu cap sigui un algoritme?