MA-CoV
Prevalence and impact of SARS-CoV-2 infection on maternal and infant health in African populations
- Duration
- 2021-2023
- Coordinator
- Raquel González (ISGlobal)
- Funded by
- EDCTP (Project code: RIA2020EF-2956)
The highest maternal mortality rates in the world are registered in sub-Saharan Africa (SSA), were the number of confirmed COVID-19 cases reported continues to increase. Information on SARS-CoV-2 and associated COVID-19 in pregnancy and their effects on maternal and perinatal health remains limited mainly to high-income countries. Thus, there is a paucity of data from SSA, where there is coexisting and highly prevalent HIV, malaria and malnutrition, and some of the poorest maternal and child health outcomes globally.
There is an urgent need to conduct surveillance and prospective studies across the region. This project aims to describe the burden and effects of SARS-CoV-2 infection during pregnancy in women living in malaria endemic areas and high prevalence of HIV infection. Pregnant women attending ANC clinics in selected sites from Libreville and Lambaréné (Gabon) and Manhiça (Mozambique) will be enrolled in a cohort study to determine the frequency of SARS-CoV-2 infection and COVID-19 during pregnancy and its effects on maternal and neonatal health.
The findings of this project will contribute to the understanding of the impact of SARS-CoV-2 and COVID-19 among pregnant women living in SSA countries where malaria and HIV infections are highly prevalent.
Budget
499,999 euros
Our Team
Principal Investigator (PI)
-
Raquel González Alvarez
ISGlobal Team
-
Azucena Bardají Associate Research Professor -
Antía Figueroa Research Technician -
Laura Garcia Otero
-
Susana Méndez Bartolomé
-
Clara Menéndez Santos
-
MIREIA PIQUERAS Project Manager
Other projects
See Past ProjectsMAMAH
Improving Maternal and Infant Health by reducing malaria risks in African women: evaluation of the safety and efficacy of dihydroartemisinin-piperaquine for intermittent preventive treatment of malaria in HIV-infected pregnant women
CaDMIA-plus
Continued validation of the minimally invasive autopsy for the investigation of the causes of death in infants, and establishment of a research and training center to study causes of death
ICARIA
Improving Care through Azithromycin Research for Infants in Africa
MIBio
Identification of Prematurity and Pre-Eclampsia as Causes of Mortality
MULTIPLY
MULTIple doses of IPTi Proposal: a Lifesaving high Yield intervention
IPERVAC-SL
Impact of perceptions of COVID-19 vaccines on health-seeking behaviours in Sierra Leone
RESPIRE
Respiratory syncytial virus (RSV) in African pregnant women and children
VITAL
Towards preparedness for new maternal vaccinations: Understanding barriers and facilitators to maternal vaccine acceptance
SARA (SARS-CoV-2 and Acetylsalicylic acid)
Efficacy of low dose acetylsalicylic acid in preventing adverse maternal and perinatal outcomes in SARS-CoV-2 infected pregnant women
HIV drug resistance (HIVDR)
Description of HIV drug resistance patterns and its association with the risk of HIV mother to child transmission among pregnant women from southern Mozambique
Evaluación de la eficacia del ácido acetilsalicílico a dosis bajas en la prevención de los efectos maternos y perinatales adversos en mujeres embarazadas infectadas por el SARS-CoV-2
PROTECT
PReparing for Optimal Phase III/IV maTErnal Group B StreptococCal vaccine Trials in Africa
