Research - Our Team

Carlos is a results-oriented global health researcher that enjoys looking at challenges from different angles. He is interested in the whole spectrum of problem solving, from discovery to scale-up and believe that open-minded multidisciplinary teams are key to innovation. His current research focus is malaria but he enjoys the full spectrum of global health.

He is a trained Internist with more than 15 years of experience. He has had clinical experience in remote indigenous communities in the venezuelan Amazon and in Mozambique.

Carlos research focus for the last 10 years has been the development of mosquito-killing drugs (endectocides) as complementary vector control strategy for malaria control and elimination. He obtained his PhD in 2015 working with slow-release ivermectin formulations for this purpose.

Carlos serves as the Co-PI and Chief Scientific Officer of the Unitaid-funded BOHEMIA project that seeks to develop ivermectin as first-in-class endectocide to reduce malaria transmission.

He holds a visiting scholar position at the Ifakara Health Institute and the University of Navarra.

Lines of research

• Malaria epidemiology
•  Malaria elimination
•  Endectocides
•  Ivermectin
•  Vector control
•  One health
•  Neglected Tropical Diseases
• Emerging viruses
• Indigenous peoples

Main publications

• Chaccour C, C, Ng´habi K, Abizanda G, Irigoyen-Barrio A, Aldaz A, Okumu F, Slater H, Del Pozo JL, Killeen G. Targeting cattle for malaria elimination: marked reduction of Anopheles arabiensis survival for over six months using a slow-release ivermectin implant formulation. Parasites & Vectors. 2018 May 4;11(1):287
• Chaccour CJ, Hammann F, Rabinovich NR: Ivermectin to reduce malaria transmission I. Pharmacokinetic and pharmacodynamic considerations regarding efficacy and safety. Malar J. 2017; 16:161
• Chaccour C, , Irigoyen A, Gil AG, Martinez D, Slater H, Hammann F, Del Pozo JL. Screening for an ivermectin slow-release formulation suitable for malaria vector control. Malar J. 2015; 14:102.
• Chaccour CJ, Kobylinski KC, Bassat Q, Bousema T, Drakeley C, Alonso P, Foy BD. Ivermectin to reduce malaria transmission: a research agenda for a promising new tool for elimination. Malar J. 2013; 12:153.
• Chaccour C, Lines J, Whitty CJ. Effect of ivermectin on Anopheles gambiae mosquitoes fed on humans: the potential of oral insecticides in malaria control. J Infect Dis. 2010; 202:113-6.
• Nicolas P, Maia MF, Bassat Q, Kobylinski KC, Monteiro W, Rabinovich R, Menéndez C, Bardají A, Chaccour C. Safety of oral ivermectin during pregnancy: a systematic review and meta-analysis. Lancet Glob Health. 2020;8(1):e92-e100. doi:10.1016/S2214-109X(19)30453-X