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Georgios Koutsoudakis

Postdoctoral Fellow

Dr. Georgios Koutsoudakis is a biomedical researcher with a strong background in molecular and cellular biology, virology and immunology acquired in 3 different countries (Germany, Italy and Spain). His scientific portfolio includes 33 scientific articles and 20 non- and competitive scientific projects (team member). During 2015-2020, his work was focused on the immunopathology caused by chronic viral hepatitis infections, and specifically on understanding mechanisms of perturbations and restoration of immune system homeostasis during and after antiviral treatments.

Of note, during the last 2.5 years, his research focused on delineating the immunopathology of patients with autoimmune hepatitis (Co-PI of the research project FIS PI021/0800). Within this grant, we has included strategies in order to analyze at a single cell resolution level the T cell repertoire infiltrated in liver biopsies of patients diagnosed with autoimmune hepatitis.

Dr. Georgios Koutsoudakis joined the Malaria Immunology group under the supervision of Prof. Carlota Dobaño and Dr. Gemma Moncunill, as a senior T cell post-doc immunologist. His future research will include analyses of i) T cell profiling in PBMCs acquired from COVID-19 cohorts and ii) T cell repertoires in malaria and helminth endemic and vaccinated populations.

Lines of research

Immunophenotyping of T cells acquired from HCW
Sars-Cov-2 responses longitudinal analysis
Comprehensive analysis of T cells in Long Covid
T cell repertoire analysis in malaria and helminth vaccinated population

Main publications

Viral and immune factors associated with successful treatment withdrawal in HBeAg-negative chronic hepatitis B patients. García-López M, Lens S, Pallett LJ, Testoni B, Rodríguez-Tajes S, Mariño Z, Bartres C, García-Pras E, Leonel T, Perpiñán E, Lozano JJ, Rodríguez-Frías F, Koutsoudakis G, Zoulim F, Maini MK, Forns X, Pérez-Del-Pulgar S. J Hepatol. 2021 May;74(5):1064-1074. doi: 10.1016/j.jhep.2020.11.043. Epub 2020 Dec 2. PMID: 33278456
Chronic genotype 1 hepatitis C along with cirrhosis drives a persistent imprint in virus-specific CD8+ T cells after direct-acting antiviral therapies. Perpiñán E, Pérez-Del-Pulgar S, Londoño MC, Mariño Z, Lens S, Leonel T, Bartres C, García-López M, Rodriguez-Tajes S, Forns X, Koutsoudakis G. J Viral Hepat. 2020 Dec;27(12):1408-1418. doi: 10.1111/jvh.13370. Epub 2020 Aug 18. PMID: 32812325
Cirrhosis Hampers Early and Rapid Normalization of Natural Killer Cell Phenotype and Function in Hepatitis C Patients Undergoing Interferon-Free Therapy. Perpiñán E, Pérez-Del-Pulgar S, Londoño MC, Mariño Z, Bartres C, González P, García-López M, Pose E, Lens S, Maini MK, Forns X, Koutsoudakis G. Front Immunol. 2020 Feb 25;11:129. doi: 10.3389/fimmu.2020.00129. eCollection 2020. PMID: 32161581
Hepatitis A outbreak in Barcelona among men who have sex with men (MSM), January-June 2017: A hospital perspective. Rodríguez-Tajes S, Perpiñán E, Caballol B, Lens S, Mariño Z, Costa J, Vilella A, Pérez-Del-Pulgar S, Forns X, Koutsoudakis G. Liver Int. 2018 Apr;38(4):588-593. doi: 10.1111/liv.13606. Epub 2017 Nov 10. PMID: 28980376
Occult Hepatitis C Virus Infection: Are We Digging Too Deep? Koutsoudakis G, Pérez-Del-Pulgar S, Forns X. Gastroenterology. 2017 Feb;152(3):472-474. doi: 10.1053/j.gastro.2016.12.015. Epub 2016 Dec 27. PMID: 28038930

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Cookies Details

Cookie	Management	Duration	Aim
COOKIE_SUPPORT	First Party	50 years	A cookie that checks whether cookies are enabled in your browser.
GUEST_LANGUAGE_ID	First Party	50 years	Cookie used to remember the user's language preferences.
JSESSIONID	First Party	Session	Cookie used to manage web applications.
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APISID	Google	2 years	Used by Google to store user preferences and information of Google
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S	Google	Session	Used by Google to store user preferences and information of Google
SAPISID	Google	2 years	Used by Google to store user preferences and information of Google
SID	Google	2 years	Used by Google to store user preferences and information of Google
SIDCC	Google	3 months	Used by Google to store user preferences and information of Google
SSID	Google	2 years	Used by Google to store user preferences and information of Google
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__Secure-3PSIDCC	Google	2 years	Used by for targeting purposes to build a profile of the website visitor's interests in order to show relevant & personalised Google advertising
CONSENT	Google	20 years	Used by Google to store user preferences and information of Google
vuid	Vimeo	2 years	A Vimeo Analytics cookie that provides a single id.
APISID	YouTube	2 years	These cookies are set via embedded YouTube videos. They register anonymous statistical data
HSID	YouTube	2 years	These cookies are set via embedded YouTube videos. They register anonymous statistical data
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PREF	YouTube	2 years	Cookie that remembers information that changes the appearance or behaviour of the web site, such as the user's preferred language or region.
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__Secure-3PAPISID	YouTube	2 years	Used by for targeting purposes to build a profile of the website visitor's interests in order to show relevant & personalised Google advertising
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__Secure-3PSIDCC	YouTube	2 years	Used by for targeting purposes to build a profile of the website visitor's interests in order to show relevant & personalised Google advertising
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ig_putma	infogram	Session	Session cookie

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Cookies Details

Cookie	Management	Duration	Aim
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Cookie	Management	Duration	Aim
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wide	YouTube	Session	These cookies are set via embedded YouTube videos. They register anonymous statistical data
s_gl	YouTube	Session