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TB-RECONNECT

Reconnecting Transmission to Global Tuberculosis Control by Mapping Pathogen Transmission Events to Host Infection Status

Duration: 01/07/2021 - 30/06/2025
Coordinator: Iñaki Comas Espadas
Funded by: European Research Council (ERC)

The aim of the TB- RECONNECT is to shed light burning questions about the nature of tuberculosis (TB) transmission and the host and pathogen biology behind it, by synergizing three recent TB research developments:

1) The use of host blood transcriptomics to discriminate between infection status within the latent pool of individuals.
2) Quantification of transmission at a resolution not previously available, using pathogen genome sequencing.
3) The application of phylogenetic and epidemiological models to identify when transmission has happened.

Combining these three key developments with TB cohorts from multiple settings, and available tools from bacterial population genetics, high-throughput functional genomics and infection biology, we will be in a key position to reconnect transmission to TB control and inform major shifts in global and local control strategies.

Total Funding

530,000 €

ISGlobal Team

Patricia Comella Research Technician
Alberto García Basteiro
Belén Saavedra Cervera

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INTE-AFRICA

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ICARIA

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PreFIT

Predicting the Future: Incipient Tuberculosis

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Stool4TB

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TwinAir

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Propagación de la resistencia en aguas

Nuevos complejos de oro (III) frente a bacterias multirresistentes

Project Code: DTS21/00004

Desarrollo de dos nuevas estrategias terapéuticas (inhibidores de bombas de expulsion y ARN antisentido) activos frente a bacterias mutliresistentes

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ENDÈMIC

Community knowledge generation through scientific culture, urban ecology and art

EpiGen

Building Scalable Pathogen Genomic Epidemiology in Ethiopia

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Eliminating hepatitis C on the Balearic Islands (Mallorca, Menorca and Ibiza): a study in governmental and non-governmental addiction service centres, a mobile methadone unit and a prison to test and link people who use drugs to HCV care.

FLAVOBAC

Nuevas moléculas de oro coordinadas con flavonoides contra bacterias patógenas multirresistentes prioritarias

Evaluación de la eficacia del ácido acetilsalicílico a dosis bajas en la prevención de los efectos maternos y perinatales adversos en mujeres embarazadas infectadas por el SARS-CoV-2

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Total Funding

Our Team

ISGlobal Team

Other projects

Cookies and privacy

Type of cookies used on the Website

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Third-party analytics cookies

Consent

Disabling and blocking cookies

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Safari (and for iOS)

Changes to the Cookies Policy

Contact