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Research

SToolNIH

Quantifiable stool-based TB PCR to Improve Diagnostics and Treatment Monitoring

Duration: 01/09/2020 - 01/09/2024
Coordinator: Anna Maria Mandalakas / Alberto García-Basteiro
Funded by: National Institutes of Health (NIH)

This project aims to validate an innovative stool homogenization and DNA isolation method that yields a highly sensitive and specific Mtb qPCR-based diagnostic. StoolTB will evaluate this platform in the high TB and HIV burden settings of Mozambique, eSwatini and Uganda under the hypothesis that it will narrow the large TB case detection gap by improving TB confirmation rates in children and people living with HIV while proving feasible and acceptable.

Total Funding

$ 2,475,880.00

Coordinators

Alberto García Basteiro
Anna Maria Mandalakas

ISGlobal Team

Lucía Carratalá Medical Research Fellow
Elisa Blanca López Varela
Belén Saavedra Cervera

Other projects

See Past Projects

COMBACTE

Combating Bacterial Resistance In Europe

GAMA

Development of Novel Gastrointestinal Biomarkers for Use in HIV Incidence Determination in a Sub-Saharan African Setting

Evaluation of Strategies for Yaws Eradication

Yaws eradication

Novel Marine Biomolecules against Biofilm (NoMorFilm)

Application to medical devices

COMBACTE-CARE

Combatting Bacterial Resistance in Europe - Carbapenem Resistance

MAMAH

Improving Maternal and Infant Health by reducing malaria risks in African women: evaluation of the safety and efficacy of dihydroartemisinin-piperaquine for intermittent preventive treatment of malaria in HIV-infected pregnant women

INTE-AFRICA

Integrating and decentralizing diabetes and hypertension services in Africa

ICARIA

Improving Care through Azithromycin Research for Infants in Africa

PreFIT

Predicting the Future: Incipient Tuberculosis

Encuesta serológica Cendea de Cizur

Cendea de Cizur

Projecte de Recerca en Resposta Immunitària i Epidemiologia de Malalties Infeccioses

Conèixer la propagació. Entendre la protecció

ANTICOV

Large Clinical Trial in Africa on the Treatment of Mild Cases of COVID-19

Stool4TB

Evaluating a new stool based qPCR for diagnosis of tuberculosis in children and people living with HIV

TB-RECONNECT

Reconnecting Transmission to Global Tuberculosis Control by Mapping Pathogen Transmission Events to Host Infection Status

ALIA - Las ciudades y la salud

Planificación urbana, medio ambiente y salud | Clima y salud | Resistencias Antimicrobianas

END-VOC

ENDing COVID-19 Variants Of concern through Cohort studies (END-VOC)

TwinAir

Digital Twins Enabled Indoor Air Quality Management for Healthy Living

Estudio de la propagación de bacterias y genes de resistencia a los antibióticos en el ciclo integral del agua, en el área metropolitana de Barcelona

Propagación de la resistencia en aguas

Nuevos complejos de oro (III) frente a bacterias multirresistentes

Project Code: DTS21/00004

Desarrollo de dos nuevas estrategias terapéuticas (inhibidores de bombas de expulsion y ARN antisentido) activos frente a bacterias mutliresistentes

Más allá de la supresión vírica del VIH: un cuarto noventa para mejorar la salud de personas viviendo con el VIH en España

Project Code: PI20/01654

ENDÈMIC

Community knowledge generation through scientific culture, urban ecology and art

EpiGen

Building Scalable Pathogen Genomic Epidemiology in Ethiopia

Hepatitis C Free Baleares

Eliminating hepatitis C on the Balearic Islands (Mallorca, Menorca and Ibiza): a study in governmental and non-governmental addiction service centres, a mobile methadone unit and a prison to test and link people who use drugs to HCV care.

FLAVOBAC

Nuevas moléculas de oro coordinadas con flavonoides contra bacterias patógenas multirresistentes prioritarias

Evaluación de la eficacia del ácido acetilsalicílico a dosis bajas en la prevención de los efectos maternos y perinatales adversos en mujeres embarazadas infectadas por el SARS-CoV-2

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Total Funding

Our Team

Coordinators

ISGlobal Team

Other projects

Cookies and privacy

Type of cookies used on the Website

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Consent

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Contact