Asset Publisher

Research & Innovation Programmes
Antimicrobial Resistance

Novel Marine Biomolecules against Biofilm (NoMorFilm)

Application to medical devices

Duration
01/04/2015 - 31/12/2019
Coordinator
Sara Soto
Funded by
Horizon 2020 (European Commission)
Website
http://www.nomorfilm.eu

Over 800,000 prostheses, and an even higher number of catheters, are inserted in patients in the European Union every year. Out of these patients, 7.5% suffer from a post-implant infection. A new surgical intervention to replace the implant is then required with a cost that oscillates between 30,000 and 50,000 euros per patient, depending on the country.

The bacteria and fungi found in infected prostheses do not respond to conventional antibiotics because these pathogens proliferate on the surfaces of the prostheses, or on the inside of the catheters, forming a microbial film called biofilm for which there is no pharmacological treatment. Hence, the search for new effective antibiotics that prevent the formation of biofilm and the resulting replacement of prostheses is of vital importance.

NoMorFilm is a project focused on the search for new biomolecules based on microalgae with antibiotic and antibiofilm activity, which could be incorporated into the prostheses or catheters during the manufacturing process, and thus avoid the complications that can arise after they have been inserted into the patient.

Our Team

Our Team

  • Sara Soto González
    Sara Soto González Associate Research Professor and Head of the Viral and Bacterial Infections Programme at ISGlobal.

Other projects

See Past Projects

COMBACTE

Combating Bacterial Resistance In Europe

GAMA

Development of Novel Gastrointestinal Biomarkers for Use in HIV Incidence Determination in a Sub-Saharan African Setting

COMBACTE-CARE

Combatting Bacterial Resistance in Europe - Carbapenem Resistance

MAMAH

Improving Maternal and Infant Health by reducing malaria risks in African women: evaluation of the safety and efficacy of dihydroartemisinin-piperaquine for intermittent preventive treatment of malaria in HIV-infected pregnant women

INTE-AFRICA

Integrating and decentralizing diabetes and hypertension services in Africa

ICARIA

Improving Care through Azithromycin Research for Infants in Africa

PreFIT

Predicting the Future: Incipient Tuberculosis

ANTICOV

Large Clinical Trial in Africa on the Treatment of Mild Cases of COVID-19

Stool4TB

Evaluating a new stool based qPCR for diagnosis of tuberculosis in children and people living with HIV

TB-RECONNECT

Reconnecting Transmission to Global Tuberculosis Control by Mapping Pathogen Transmission Events to Host Infection Status

SToolNIH

Quantifiable stool-based TB PCR to Improve Diagnostics and Treatment Monitoring

END-VOC

ENDing COVID-19 Variants Of concern through Cohort studies (END-VOC)

TwinAir

Digital Twins Enabled Indoor Air Quality Management for Healthy Living

ENDÈMIC

Community knowledge generation through scientific culture, urban ecology and art

EpiGen

Building Scalable Pathogen Genomic Epidemiology in Ethiopia

Hepatitis C Free Baleares

Eliminating hepatitis C on the Balearic Islands (Mallorca, Menorca and Ibiza): a study in governmental and non-governmental addiction service centres, a mobile methadone unit and a prison to test and link people who use drugs to HCV care.

FLAVOBAC

Nuevas moléculas de oro coordinadas con flavonoides contra bacterias patógenas multirresistentes prioritarias