Viral and Bacterial Infections
Although mortality from infectious disease has declined globally, viral and bacterial infections still disproportionately impact the world's most vulnerable populations. Pneumonia and diarrhoea are major killers in young children while syphilis is the main cause of stillbirth and perinatal mortality. HIV, tuberculosis, and viral hepatitis are among the leading causes of deaths due to infectious disease in adults living in low and middle income countries. Treatment for these devastating diseases exists, but their use and effectiveness face numerous challenges including timely diagnosis, drug resistance and access to healthcare. Sub-Saharan Africa is home to 70% of the world’s people living with HIV and the highest tuberculosis burden in the world. Although treatment has saved many lives, daunting challenges in reaching, diagnosing and treating patients hamper their control.
Multi-resistant bacteria are found in all regions of the world and spread easily, thus constituting one of the most serious threats to global health. In the last decades, emerging infectious diseases, especially those related to emerging viruses such as dengue, chikungunya and Zika, have become an increasingly important area of concern in public health at a global level. The crisis triggered by SARS-CoV-2, the coronavirus responsible for COVID-19, has brought the threat of emerging viruses to the forefront at a global level.
Main research lines
At ISGlobal, we use our experience to improve the diagnosis and treatment of viral and bacterial diseases, to understand the causes of antibiotic resistance, and to find novel ways of reaching underserved populations in the following areas:
Our Team
Head
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Sara Soto González Associate Research Professor and Head of the Viral and Bacterial Infections Programme at ISGlobal.
Co-directors
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Jeffrey Lazarus Head of the Public Health Liver Group
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Jordi Vila Estapé Research Professor and Director of the Antimicrobial Resistance Initiative
Our Team
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Quique Bassat Director General
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Climent Casals-Pascual Associate Research Professor
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Alberto García-Basteiro Associate Research Professor
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Julià González Associated Researcher
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Emili Letang Associated Researcher
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Mª Ángeles Marcos Associate Researcher
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Miguel J. Martínez Yoldi
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DENISE NANICHE Scientific Director
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Ignasi Roca Associated Researcher
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Antoni Trilla Research Professor, Dean of the Faculty of Medicina and Health Sciences, UB
Highlighted Projects
Projecte de Recerca en Resposta Immunitària i Epidemiologia de Malalties Infeccioses
Conèixer la propagació. Entendre la protecció
ANTICOV
Large Clinical Trial in Africa on the Treatment of Mild Cases of COVID-19
Más allá de la supresión vírica del VIH: un cuarto noventa para mejorar la salud de personas viviendo con el VIH en España
Project Code: PI20/01654
Desarrollo de dos nuevas estrategias terapéuticas (inhibidores de bombas de expulsion y ARN antisentido) activos frente a bacterias mutliresistentes
Nuevos complejos de oro (III) frente a bacterias multirresistentes
Project Code: DTS21/00004
Hepatitis C Free Baleares
Eliminating hepatitis C on the Balearic Islands (Mallorca, Menorca and Ibiza): a study in governmental and non-governmental addiction service centres, a mobile methadone unit and a prison to test and link people who use drugs to HCV care.
END-VOC
ENDing COVID-19 Variants Of concern through Cohort studies (END-VOC)
Stool4TB
Evaluating a new stool based qPCR for diagnosis of tuberculosis in children and people living with HIV
INTE-AFRICA
Integrating and decentralizing diabetes and hypertension services in Africa
Novel Marine Biomolecules against Biofilm (NoMorFilm)
Application to medical devices
Evaluation of Strategies for Yaws Eradication
Yaws eradication
COMBACTE-CARE
Combatting Bacterial Resistance in Europe - Carbapenem Resistance
Other projects
See Past ProjectsPreFIT
Predicting the Future: Incipient Tuberculosis
Predicting the Future: Incipient Tuberculosis
TB-RECONNECT
Reconnecting Transmission to Global Tuberculosis Control by Mapping Pathogen Transmission Events to Host Infection Status
Estudio de la propagación de bacterias y genes de resistencia a los antibióticos en el ciclo integral del agua, en el área metropolitana de Barcelona
Propagación de la resistencia en aguas
ENDÈMIC
Community knowledge generation through scientific culture, urban ecology and art
EpiGen
Building Scalable Pathogen Genomic Epidemiology in Ethiopia
FLAVOBAC
Nuevas moléculas de oro coordinadas con flavonoides contra bacterias patógenas multirresistentes prioritarias