Edson Tereso Vany Francisco Mambuque is an experienced microbiologist with a strong background in medical microbiology and infectious disease research. He holds a Master's degree in Medical Microbiology from the NOVA School of Science and Technology (2019-2021) and a degree in Biology from the Universidade Pedagógica, Maputo. His academic journey is complemented by specialised training in biosafety, clinical laboratory practice and tuberculosis research.
With over a decade of experience, Edson has played a key role in microbiology and disease surveillance. Since 2015, he has been part of the Centro de Investigação em Saúde de Manhiça (CISM), where he currently serves as TB laboratory manager. In this role, he oversees laboratory operations, ensures diagnostic accuracy and implements quality control measures for tuberculosis research and diagnostics. His expertise includes molecular diagnostics, trial coordination and laboratory management.
Previously, he contributed to public health efforts at the National Microbiology Reference Laboratory and coordinated clinical trials at the Research Centre for Infectious Diseases, Catholic University of Mozambique. An active researcher, he has co-authored several publications on tuberculosis diagnostics and drug resistance. Through his work, Edson remains committed to improving laboratory standards and advancing infectious disease research in Mozambique.
Línies de recerca
- Infectious Disease and Tuberculosis
- Antibiotics and Drug resistances
- Tropical diseases
Publicacions principals
- Carratalà-Castro L, Munguambe S, Saavedra-Cervera B, de Haas P, Kay A, MarcyO, Nabeta P, Ssengooba W, Ghimenton-Walters E, Acácio S, Bonnet M, Ehrlich J,DiNardo AR, Vasiliu A, Lange C, Hermans S, Mandalakas AM, López-Varela E,García-Basteiro AL; Stool4TB Global Partnership. Performance of stool-basedmolecular tests and processing methods for paediatric tuberculosis diagnosis: asystematic review and meta-analysis. Lancet Microbe. 2024 Nov 9:100963. doi:10.1016/j.lanmic.2024.100963. Epub ahead of print. PMID: 39547244.
- Kasule GW, Hermans S, Semugenze D, Wekiya E, Nsubuga J, Mwachan P, Kabugo J,Joloba M, García-Basteiro AL, Ssengooba W; Stool4TB Global Partnership. Non-sputum-based samples and biomarkers for detection of Mycobacterium tuberculosis:the hope to improve childhood and HIV-associated tuberculosis diagnosis. Eur J Med Res. 2024 Oct 18;29(1):502. doi: 10.1186/s40001-024-02092-z. PMID: 39420420;PMCID: PMC11487833.
- Kay A, Vasiliu A, Carratala-Castro L, Mtafya B, Mendez Reyes JE, Maphalala N,Munguambe S, Mulengwa D, Ness T, Saavedra B, Bacha J, Maphalala G, Mejia R,Mtetwa G, Acacio S, Manjate P, Mambuque E, Shiba N, Kota N, Ziyane M, NtinginyaNE, Lange C, Kirchner HL, DiNardo AR, Garcia-Basteiro AL, Mandalakas AM;Stool4TB Global Partnership. Performance of a stool-based quantitative PCR assay for the diagnosis of tuberculosis in adolescents and adults: a multinational, prospective diagnostic accuracy study. Lancet Microbe. 2024 May;5(5):e433-e441. doi: 10.1016/S2666-5247(23)00391-9. Epub 2024 Mar 7. PMID: 38461830; PMCID: PMC11142891.
- Carratala-Castro L, Ssengooba W, Kay A, Acácio S, Ehrlich J, DiNardo AR, Shiba N, Nsubuga JK, Munguambe S, Saavedra-Cervera B, Manjate P, Mulengwa D, Sibandze B, Ziyane M, Kasule G, Mambuque E, Sekadde MP, Wobudeya E, Joloba ML, Heyckendorf J, Lange C, Hermans S, Mandalakas A, García-Basteiro AL, Lopez- Varela E; Stool4TB Global Partnership. A stool based qPCR for the diagnosis of TB in children and people living with HIV in Uganda, Eswatini and Mozambique (Stool4TB): a protocol for a multicenter diagnostic evaluation. BMC Infect Dis. 2024 Feb 21;24(1):233. doi: 10.1186/s12879-023-08708-9. PMID: 38383310; PMCID: PMC10880221.
- Mambuque E, Saavedra B, Molina-Moya B, Nguenha D, García-García E, Blanco S, Gomes N, Ehrlich J, Bulo H, Munguambe S, Chiconela H, Acacio S, Domínguez J, García-Basteiro AL. Evaluation of Omnigene-Sputum for Preservation of Sputum Samples for Diagnosis of <i>Mycobacterium tuberculosis</i>. Trop Med Infect Dis. 2023 Jul 17;8(7):367. doi: 10.3390/tropicalmed8070367. PMID: 37505663; PMCID: PMC10386065.
- Mariner-Llicer C, Saavedra Cervera B, Mambuque E, Gomes N, Munguambe S, Villamayor L, Cancino-Muñoz I, Torres-Puente M, Nguenha D, Respeito D, Tembe G, López MG, Comas I, García-Basteiro AL. Monitoring of First-line Drug Resistance Mutations Outside the Scope of Xpert MTB/RIF Ultra is Needed for Successful Control of DR-TB in Southern Mozambique. Clin Infect Dis. 2024 Apr 10;78(4):842-845. doi: 10.1093/cid/ciad684. PMID: 38048599; PMCID: PMC11006097
