Equip ISGlobal

Dinis Nguenha is a medical doctor and a PhD student at the Amsterdam Institute for Global Health and Development (AIGHD) and ISGlobal. He is an assistant researcher with experience leading and supervising clinical study teams. His work actively contributes to the Ministry of Health’s National Quality Improvement Program, promoting implementation science research to generate practical, evidence-based solutions for critical public health challenges.

His research focuses on the clinical epidemiology of tuberculosis, with a strong emphasis on developing innovative diagnostic tools, treatments, and vaccines. His work is particularly relevant in the context of emerging TB vaccine research. He is also dedicated to improving methods for estimating TB disease burden and advancing the understanding of tuberculosis from microbiological, clinical, and societal perspectives.

Línies de recerca

• Clinical Epidemiology of Tuberculosis
• TB Vaccines
• TB Diagnostics
• TB and Undernutrition
• TB Treatment Strategies

Publicacions principals

• Dinis Nguenha, Felex Ndebele, Belen Saavedra1, Edson Mambuque, Sozinho Acácio, Vicky Cárdenas, Violet Chihota, Alison Grant, Getnet Yimer, Katherine Fielding, Frank Cobelens, Gavin Churchyard, Alberto Garcia-Basteiro. BMI as a predictor of progression from TB infection to active TB in PLHIV: secondary analysis of the WHIP3TB trial.  Int J Tuberc Lung Dis. 2024. Accepted for publication. 
• Dinis Nguenha, Sozinho Acacio, Adrià Murias-Closas, Nehaben Ramanlal, Belén Saavedra, Esmeralda Karajeanes, Benilde Mudumane, Edson Mambuque, Neide Gomes, Irene Losada, Laura Oliveras, Eva Naueia, Timothy R. Sterling, Gustavo Amorim, Troy Moon, Clara Menéndez, Paula Vaz, Elisa López-Varela, Alberto L. Garcia-Basteiro. Prevalence and clinical characteristics of tuberculosis among pre- and post-partum pregnant women living in Mozambique. INT J TUBERC LUNG DIS 26(7):641–649; 2022; doi.org/10.5588/ijtld.21.0567. 
• Dinis Nguenha, Marta Cossa, Sozinho Acacio, Alberto L. Garcia-Basteiro. Scaling up shorter TB preventive treatment is long overdue. INT J TUBERC LUNG DIS 26(8):699–701, 2022; doi.org/10.5588/ijtld.22.0284. 
• Gavin Churchyard, Vicky Cardenas, Violet Chihota, Kathy Mngadi, Modulakgotla Sebe, William Brumskine, Neil Martinson, Getnet Yimer, Shu-Hua Wang, Alberto L. Garcia-Basteiro, Dinis Nguenha, LeeAnne Masilela, Zainab Waggie, Susan van den Hof, Salome Charalambous, Frank Cobelens, Richard E. Chaisson, Alison D. Grant, Katherine L Fielding and the WHIP3TB study team. Annual Tuberculosis Preventive Therapy for Persons with HIV Infection- A Randomized Trial. Annals of Internal Medicine 2021; doi.org/10.7326/M20-7577.
• Saavedra B, Nguenha D, de la Torre-Pérez L, Mambuque E, Tembe G, Oliveras L, Rudd M, Philimone P, Jose B, Garcia JI, Gomes N, Munguambe S, Chiconela H, Nhanommbe M, Izco S, Acacio S, García-Basteiro AL. Improving tuberculosis case detection through contact risk stratification by Xpert MTB/RIF Ultra and spatial parameters: Evaluation of an innovative active case finding strategy in Mozambique (Xpatial-TB). PLOS Glob Public Health. 2024 Feb 9;4(2): e0002789. doi: 10.1371/journal.pgph.0002789. PMID: 38335231; PMCID: PMC10857722.